Show simple item record

dc.contributor.authorEvans, D
dc.contributor.authorWoodward, E
dc.contributor.authorHarkness, E
dc.contributor.authorHowell, Anthony
dc.contributor.authorPlaskocinska, I
dc.contributor.authorMaher, E
dc.contributor.authorTischkowitz, M
dc.contributor.authorLalloo, F
dc.date.accessioned2018-04-28T20:50:37Z
dc.date.available2018-04-28T20:50:37Z
dc.date.issued2018-02-26
dc.identifier.citationPenetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing: a new unbiased method to assess risk? 2018, J Med Geneten
dc.identifier.issn1468-6244
dc.identifier.pmid29483236
dc.identifier.doi10.1136/jmedgenet-2017-105223
dc.identifier.urihttp://hdl.handle.net/10541/620916
dc.description.abstractThe identification of BRCA1, BRCA2 or mismatch repair (MMR) pathogenic gene variants in familial breast/ovarian/colorectal cancer families facilitates predictive genetic testing of at-risk relatives. However, controversy still exists regarding overall lifetime risks of cancer in individuals testing positive.
dc.language.isoenen
dc.rightsArchived with thanks to Journal of medical geneticsen
dc.titlePenetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing: a new unbiased method to assess risk?en
dc.typeArticleen
dc.contributor.departmentDivision of Evolution and Genomic Science, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, Manchester, UKManchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UKen
dc.identifier.journalJournal of Medical Geneticsen
html.description.abstractThe identification of BRCA1, BRCA2 or mismatch repair (MMR) pathogenic gene variants in familial breast/ovarian/colorectal cancer families facilitates predictive genetic testing of at-risk relatives. However, controversy still exists regarding overall lifetime risks of cancer in individuals testing positive.


This item appears in the following Collection(s)

Show simple item record