Show simple item record

dc.contributor.authorPathmanathan, Aen
dc.contributor.authorvan As, Nen
dc.contributor.authorKerkmeijer, Len
dc.contributor.authorChristodouleas, Jen
dc.contributor.authorLawton, Cen
dc.contributor.authorVesprini, Den
dc.contributor.authorvan der Heide, Uen
dc.contributor.authorFrank, Sen
dc.contributor.authorNill, Sen
dc.contributor.authorOelfke, Uen
dc.contributor.authorvan Herk, Marcelen
dc.contributor.authorLi, Xen
dc.contributor.authorMittauer, Ken
dc.contributor.authorRitter, Men
dc.contributor.authorChoudhury, Ananyaen
dc.contributor.authorTree, Alison Cen
dc.date.accessioned2018-02-08T13:25:02Z
dc.date.available2018-02-08T13:25:02Z
dc.date.issued2018-02-01
dc.identifier.citationMagnetic resonance imaging-guided adaptive radiation therapy: A 'game changer' for prostate treatment? 2018, 100 (2):361-373 Int J Radiat Oncol Biol Physen
dc.identifier.issn1879-355X
dc.identifier.pmid29353654
dc.identifier.doi10.1016/j.ijrobp.2017.10.020
dc.identifier.urihttp://hdl.handle.net/10541/620815
dc.description.abstractRadiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator allows for accurate soft tissue tracking with the capacity to replan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MRI-only workflow, and real-time adaptive planning. The present report reviews the steps involved in hypofractionated adaptive MRI-guided prostate radiation therapy and addresses the challenges for implementation.
dc.language.isoenen
dc.rightsArchived with thanks to International journal of radiation oncology, biology, physicsen
dc.titleMagnetic resonance imaging-guided adaptive radiation therapy: A 'game changer' for prostate treatment?en
dc.typeArticleen
dc.contributor.departmentThe Institute of Cancer Research, London, United Kingdomen
dc.identifier.journalInternational Journal of Radiation Oncology, Biology, Physicsen
refterms.dateFOA2018-12-17T15:13:36Z
html.description.abstractRadiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator allows for accurate soft tissue tracking with the capacity to replan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MRI-only workflow, and real-time adaptive planning. The present report reviews the steps involved in hypofractionated adaptive MRI-guided prostate radiation therapy and addresses the challenges for implementation.


Files in this item

Thumbnail
Name:
PIIS0360301617340269.pdf
Size:
1.153Mb
Format:
PDF
Description:
Open access full text article

This item appears in the following Collection(s)

Show simple item record