Magnetic resonance imaging-guided adaptive radiation therapy: A 'game changer' for prostate treatment?
van As, N
van der Heide, U
van Herk, Marcel
Tree, Alison C
AffiliationThe Institute of Cancer Research, London, United Kingdom
MetadataShow full item record
AbstractRadiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator allows for accurate soft tissue tracking with the capacity to replan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MRI-only workflow, and real-time adaptive planning. The present report reviews the steps involved in hypofractionated adaptive MRI-guided prostate radiation therapy and addresses the challenges for implementation.
CitationMagnetic resonance imaging-guided adaptive radiation therapy: A 'game changer' for prostate treatment? 2018, 100 (2):361-373 Int J Radiat Oncol Biol Phys
JournalInternational Journal of Radiation Oncology, Biology, Physics