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dc.contributor.authorGermano, G
dc.contributor.authorMauri, G
dc.contributor.authorSiravegna, G
dc.contributor.authorDive, Caroline
dc.contributor.authorPierce, Jackie
dc.contributor.authorDi Nicolantonio, F
dc.contributor.authorD'Incalci, M
dc.contributor.authorBardelli, A
dc.contributor.authorSiena, S
dc.contributor.authorSartore-Bianchi, A
dc.date.accessioned2018-01-14T18:44:44Z
dc.date.available2018-01-14T18:44:44Z
dc.date.issued2017-11-01
dc.identifier.citationParallel evaluation of circulating tumor DNA and circulating tumor cells in metastatic colorectal cancer. 2017, Clin Colorectal Canceren
dc.identifier.issn1938-0674
dc.identifier.pmid29195807
dc.identifier.doi10.1016/j.clcc.2017.10.017
dc.identifier.urihttp://hdl.handle.net/10541/620777
dc.description.abstractTissue biopsy is the gold standard for tumor genotyping, but it is an invasive procedure providing a single snapshot into tumor heterogeneity. Liquid biopsy approaches, encompassing the analysis of circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs), have been proposed as an alternative, with the potential of providing a comprehensive portrait of the tumor molecular landscape. In metastatic colorectal cancer (mCRC), both CTCs and ctDNA analysis have been investigated, but comparative analyses are limited.
dc.language.isoenen
dc.rightsArchived with thanks to Clinical colorectal canceren
dc.titleParallel evaluation of circulating tumor DNA and circulating tumor cells in metastatic colorectal cancer.en
dc.typeArticleen
dc.contributor.departmentCandiolo Cancer Institute-FPO, IRCCS, Candiolo (TO), Italyen
dc.identifier.journalClinical Colorectal Canceren
html.description.abstractTissue biopsy is the gold standard for tumor genotyping, but it is an invasive procedure providing a single snapshot into tumor heterogeneity. Liquid biopsy approaches, encompassing the analysis of circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs), have been proposed as an alternative, with the potential of providing a comprehensive portrait of the tumor molecular landscape. In metastatic colorectal cancer (mCRC), both CTCs and ctDNA analysis have been investigated, but comparative analyses are limited.


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