Taxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status.
Authors
Lowe, Natalie MBernstein, Jonathan M
Mais, Kathleen L
Garcez, Kate
Lee, Lip W
Sykes, Andrew J
Thomson, David J
Homer, Jarrod J
West, Catharine M L
Slevin, Nicholas J
Affiliation
Translational Radiobiology Group, Division of Cancer Sciences, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, The Christie NHS Foundation Trust, University of Manchester, Wilmslow Road, ManchesterIssue Date
2017-12-08
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The benefit of adding docetaxel, cisplatin and 5-fluorouracil (TPF) induction chemotherapy to chemoradiotherapy (CRT) in head and neck squamous cell carcinoma (HNSCC) remains uncertain. We aimed to investigate whether ICT is well tolerated when given with prophylactic treatment against predicted adverse effects and which patients benefit most.Citation
Taxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status. 2017, J Cancer Res Clin OncolJournal
Journal of Cancer Research and Clinical OncologyDOI
10.1007/s00432-017-2553-9PubMed ID
29222650Type
ArticleLanguage
enISSN
1432-1335ae974a485f413a2113503eed53cd6c53
10.1007/s00432-017-2553-9
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