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    Taxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status.

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    Authors
    Lowe, Natalie M
    Bernstein, Jonathan M
    Mais, Kathleen L
    Garcez, Kate
    Lee, Lip W
    Sykes, Andrew J
    Thomson, David J
    Homer, Jarrod J
    West, Catharine M L
    Slevin, Nicholas J
    Affiliation
    Translational Radiobiology Group, Division of Cancer Sciences, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, The Christie NHS Foundation Trust, University of Manchester, Wilmslow Road, Manchester
    Issue Date
    2017-12-08
    
    Metadata
    Show full item record
    Abstract
    The benefit of adding docetaxel, cisplatin and 5-fluorouracil (TPF) induction chemotherapy to chemoradiotherapy (CRT) in head and neck squamous cell carcinoma (HNSCC) remains uncertain. We aimed to investigate whether ICT is well tolerated when given with prophylactic treatment against predicted adverse effects and which patients benefit most.
    Citation
    Taxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status. 2017, J Cancer Res Clin Oncol
    Journal
    Journal of Cancer Research and Clinical Oncology
    URI
    http://hdl.handle.net/10541/620765
    DOI
    10.1007/s00432-017-2553-9
    PubMed ID
    29222650
    Type
    Article
    Language
    en
    ISSN
    1432-1335
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00432-017-2553-9
    Scopus Count
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