Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients.
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Authors
Valpione, SaraGremel, Gabriela
Mundra, P A
Middlehurst, P
Galvani, Elena
Girotti, Maria Romina
Lee, Rebecca J
Garner, G
Dhomen, Nathalie
Lorigan, Paul C
Marais, Richard
Affiliation
Molecular Oncology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester, M20 4GJ, UKIssue Date
2017-11-23
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Tumour burden is a prognostic biomarker in metastatic melanoma. However, tumour burden is difficult to measure and there are currently no reliable surrogate biomarkers to easily and reliably determine it. The aim of this study was to assess the potential of plasma total cell free DNA as biomarker of tumour burden and prognosis in metastatic melanoma patients.Citation
Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients. 2017, 88:1-9 Eur J CancerJournal
European Journal of CancerDOI
10.1016/j.ejca.2017.10.029PubMed ID
29175734Type
ArticleLanguage
enISSN
1879-0852ae974a485f413a2113503eed53cd6c53
10.1016/j.ejca.2017.10.029
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