Indoor tanning and melanoma risk: long-term evidence from a prospective population-based cohort study.
AffiliationOslo Centre for Biostatistics and Epidemiology, Institute of Basic Medical Sciences, University of Oslo, Blindern,Oslo, Norway
MetadataShow full item record
AbstractIndoor tanning is associated with increased risk of melanoma, but most evidence comes from case-control studies. Using data from the Norwegian Women and Cancer Study, a large prospective cohort study, we investigated the associations of age at initiation of indoor tanning, duration of tanning-device use, and dose response with melanoma risk and examined the role of indoor tanning in age at melanoma diagnosis. We used Poisson regression to estimate relative risks and 95% confidence intervals for the relationship of indoor tanning to melanoma risk and linear regression to examine age of indoor tanning initiation in relation to age at diagnosis. During follow-up of 141,045 women (1991-2012; mean duration follow-up = 13.7 years), 861 women were diagnosed with melanoma. Melanoma risk increased with increasing cumulative number of tanning sessions (for highest tertile of use vs. never use, adjusted relative risk = 1.32, 95% confidence interval (CI): 1.08, 1.63); P-trend = 0.006. Age at initiation <30 years was associated with a higher risk in comparison with never use (adjusted relative risk = 1.31, 95% CI: 1.07, 1.59). Moreover, women who started indoor tanning prior to 30 years of age were 2.2 years (95% CI: 0.9, 3.4) younger at diagnosis, on average, than never users. This cohort study provides strong evidence of a dose-response association between indoor tanning and risk of melanoma and supports the hypothesis that vulnerability to the harmful effects of indoor tanning is greater at a younger age.
CitationIndoor tanning and melanoma risk: long-term evidence from a prospective population-based cohort study. 2017, 185 (3):147-156 Am J Epidemiol
JournalAmerican Journal of Epidemiology
- Association Between Indoor Tanning and Melanoma in Younger Men and Women.
- Authors: Lazovich D, Isaksson Vogel R, Weinstock MA, Nelson HH, Ahmed RL, Berwick M
- Issue date: 2016 Mar
- Host characteristics, sun exposure, indoor tanning and risk of squamous cell carcinoma of the skin.
- Authors: Veierød MB, Couto E, Lund E, Adami HO, Weiderpass E
- Issue date: 2014 Jul 15
- Indoor tanning and risk of melanoma: a case-control study in a highly exposed population.
- Authors: Lazovich D, Vogel RI, Berwick M, Weinstock MA, Anderson KE, Warshaw EM
- Issue date: 2010 Jun
- Indoor tanning in businesses and homes and risk of melanoma and nonmelanoma skin cancer in 2 US case-control studies.
- Authors: Ferrucci LM, Vogel RI, Cartmel B, Lazovich D, Mayne ST
- Issue date: 2014 Nov
- Association of Lifetime Indoor Tanning and Subsequent Risk of Cutaneous Squamous Cell Carcinoma.
- Authors: Lergenmuller S, Ghiasvand R, Robsahm TE, Green AC, Lund E, Rueegg CS, Veierød MB
- Issue date: 2019 Oct 2