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    Higher expression of activation-induced cytidine deaminase is significantly associated with Merkel cell polyomavirus-negative Merkel cell carcinomas.

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    Authors
    Matsushita, M
    Iwasaki, T
    Nonaka, Daisuke
    Kuwamoto, S
    Nagata, K
    Kato, M
    Kitamura, Y
    Hayashi, K
    Affiliation
    Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan
    Issue Date
    2017-09
    
    Metadata
    Show full item record
    Abstract
    Merkel cell carcinomas (MCCs), clinically aggressive neuroendocrine skin cancers, are divided into Merkel cell polyomavirus (MCPyV)-positive and -negative tumors, which show different clinicopathological features and may develop through different mechanisms of carcinogenesis. Aberrant expression of activation-induced cytidine deaminase (AID) as a genomic modulator was demonstrated through pathogen-related NF-κB signal in Helicobacter pylori-associated gastric cancer, adult T cell leukemia/lymphoma (HTLV-1), hepatoma (HCV), and Burkitt lymphoma (EBV).
    Citation
    Higher expression of activation-induced cytidine deaminase is significantly associated with Merkel cell polyomavirus-negative Merkel cell carcinomas. 2017, 60 (3):145-153 Yonago Acta Med
    Journal
    Yonago Acta Medica
    URI
    http://hdl.handle.net/10541/620616
    PubMed ID
    28959124
    Type
    Article
    Language
    en
    ISSN
    0513-5710
    Collections
    All Christie Publications

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