Pathology update to the Manchester Scoring System based on testing in over 4000 families.
Authors
Evans, D Gareth RHarkness, E
Plaskocinska, I
Wallace, A
Clancy, T
Woodward, E
Howell, Anthony
Tischkowitz, M
Lalloo, F
Affiliation
Prevent Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Foundation Trust, Wythenshawe, Manchester, UKIssue Date
2017-05-10
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Show full item recordAbstract
While the requirement for thresholds for testing for mutations in BRCA1/2 is being questioned, they are likely to remain for individuals unaffected by a relevant cancer. It is still useful to provide pretesting likelihoods, but models need to take into account tumour pathology.Citation
Pathology update to the Manchester Scoring System based on testing in over 4000 families. 2017 J Med GenetJournal
Journal of Medical GeneticsDOI
10.1136/jmedgenet-2017-104584PubMed ID
28490612Type
ArticleLanguage
enISSN
1468-6244ae974a485f413a2113503eed53cd6c53
10.1136/jmedgenet-2017-104584
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