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    Pathology update to the Manchester Scoring System based on testing in over 4000 families.

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    Authors
    Evans, D Gareth R
    Harkness, E
    Plaskocinska, I
    Wallace, A
    Clancy, T
    Woodward, E
    Howell, Anthony
    Tischkowitz, M
    Lalloo, F
    Affiliation
    Prevent Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Foundation Trust, Wythenshawe, Manchester, UK
    Issue Date
    2017-05-10
    
    Metadata
    Show full item record
    Abstract
    While the requirement for thresholds for testing for mutations in BRCA1/2 is being questioned, they are likely to remain for individuals unaffected by a relevant cancer. It is still useful to provide pretesting likelihoods, but models need to take into account tumour pathology.
    Citation
    Pathology update to the Manchester Scoring System based on testing in over 4000 families. 2017 J Med Genet
    Journal
    Journal of Medical Genetics
    URI
    http://hdl.handle.net/10541/620405
    DOI
    10.1136/jmedgenet-2017-104584
    PubMed ID
    28490612
    Type
    Article
    Language
    en
    ISSN
    1468-6244
    ae974a485f413a2113503eed53cd6c53
    10.1136/jmedgenet-2017-104584
    Scopus Count
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