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    Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK Medical Research Council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial.

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    Authors
    Cunningham, D
    Stenning, S
    Smyth, E
    Okines, A
    Allum, W
    Rowley, S
    Stevenson, L
    Grabsch, H
    Alderson, D
    Crosby, T
    Griffin, S
    Mansoor, Was
    Coxon, F
    Falk, S
    Darby, S
    Sumpter, K
    Blazeby, J
    Langley, R
    Show allShow less
    Affiliation
    Department of Oncology, Royal Marsden NHS Foundation Trust, London, UK
    Issue Date
    2017-02-02
    
    Metadata
    Show full item record
    Abstract
    Peri-operative chemotherapy and surgery is a standard of care for patients with resectable oesophagogastric adenocarcinoma. Bevacizumab, a monoclonal antibody against VEGF, improves the proportion of patients responding to treatment in advanced gastric cancer. We aimed to assess the safety and efficacy of adding bevacizumab to peri-operative chemotherapy in patients with resectable gastric, oesophagogastric junction, or lower oesophageal adenocarcinoma.
    Citation
    Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK Medical Research Council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial. 2017, Lancet Oncol
    Journal
    The Lancet Oncology
    URI
    http://hdl.handle.net/10541/620160
    DOI
    10.1016/S1470-2045(17)30043-8
    PubMed ID
    28163000
    Type
    Article
    Language
    en
    ISSN
    1474-5488
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1470-2045(17)30043-8
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