Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels.
dc.contributor.author | Valassi, E | |
dc.contributor.author | Crespo, I | |
dc.contributor.author | Keevil, B | |
dc.contributor.author | Aulinas, A | |
dc.contributor.author | Urgell, E | |
dc.contributor.author | Santos, A | |
dc.contributor.author | Trainer, Peter J | |
dc.contributor.author | Webb, S | |
dc.date.accessioned | 2017-01-13T10:24:05Z | |
dc.date.available | 2017-01-13T10:24:05Z | |
dc.date.issued | 2017-02 | |
dc.identifier.citation | Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels. 2017, 176 (2):221-231 Eur J Endocrinol | en |
dc.identifier.issn | 1479-683X | |
dc.identifier.pmid | 27932530 | |
dc.identifier.doi | 10.1530/EJE-16-0779 | |
dc.identifier.uri | http://hdl.handle.net/10541/620078 | |
dc.description.abstract | Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were to assess affective alterations after long-term remission of CS and evaluate whether they are associated with serum BDNF, salivary cortisol (SalF) and/or cortisone (SalE) concentrations. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to European journal of endocrinology | en |
dc.title | Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels. | en |
dc.type | Article | en |
dc.contributor.department | Endocrinology/Medicine DepartmentHospital Sant Pau, Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER, Unidad 747), IIB-Sant Pau, ISCIII and Universitat Autonoma de Barcelona (UAB), Barcelona | en |
dc.identifier.journal | European Journal of Endocrinology | en |
refterms.dateFOA | 2020-04-21T08:22:30Z | |
html.description.abstract | Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were to assess affective alterations after long-term remission of CS and evaluate whether they are associated with serum BDNF, salivary cortisol (SalF) and/or cortisone (SalE) concentrations. |