Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels.
Affiliation
Endocrinology/Medicine DepartmentHospital Sant Pau, Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER, Unidad 747), IIB-Sant Pau, ISCIII and Universitat Autonoma de Barcelona (UAB), BarcelonaIssue Date
2017-02
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Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were to assess affective alterations after long-term remission of CS and evaluate whether they are associated with serum BDNF, salivary cortisol (SalF) and/or cortisone (SalE) concentrations.Citation
Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels. 2017, 176 (2):221-231 Eur J EndocrinolJournal
European Journal of EndocrinologyDOI
10.1530/EJE-16-0779PubMed ID
27932530Type
ArticleLanguage
enISSN
1479-683Xae974a485f413a2113503eed53cd6c53
10.1530/EJE-16-0779
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