Necitumumab plus gemcitabine and cisplatin as first-line therapy in patients with stage IV EGFR- expressing squamous non-small-cell lung cancer: German subgroup data from an open-label, randomized controlled phase 3 study (SQUIRE).
dc.contributor.author | Reck, M | |
dc.contributor.author | Thomas, M | |
dc.contributor.author | Kropf-Sanchen, C | |
dc.contributor.author | Mezger, J | |
dc.contributor.author | Socinski, M A | |
dc.contributor.author | Depenbrock, H | |
dc.contributor.author | Soldatenkova, V | |
dc.contributor.author | Brown, J | |
dc.contributor.author | Krause, T | |
dc.contributor.author | Thatcher, Nick | |
dc.date.accessioned | 2016-12-16T15:35:35Z | |
dc.date.available | 2016-12-16T15:35:35Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Necitumumab plus gemcitabine and cisplatin as first-line therapy in patients with stage IV EGFR- expressing squamous non-small-cell lung cancer: German subgroup data from an open-label, randomized controlled phase 3 study (SQUIRE). 2016, 39(9): 539-47 Oncol Res Treat | en |
dc.identifier.issn | 2296-5262 | |
dc.identifier.pmid | 27614872 | |
dc.identifier.doi | 10.1159/000448085 | |
dc.identifier.uri | http://hdl.handle.net/10541/620051 | |
dc.description.abstract | In the SQUIRE study, adding the anti-epidermal growth factor receptor (EGFR) IgG1 antibody necitumumab to first-line gemcitabine and cisplatin (GC + N) in advanced squamous non-small-cell lung cancer (sqNSCLC) significantly improved overall survival (OS); the safety profile was acceptable. We explored data for the German subpopulation (N = 96) of SQUIRE patients with EGFR-expressing tumors. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to Oncology research and treatment | en |
dc.title | Necitumumab plus gemcitabine and cisplatin as first-line therapy in patients with stage IV EGFR- expressing squamous non-small-cell lung cancer: German subgroup data from an open-label, randomized controlled phase 3 study (SQUIRE). | en |
dc.type | Article | en |
dc.identifier.journal | Oncology research and treatment | en |
refterms.dateFOA | 2018-12-17T14:46:13Z | |
html.description.abstract | In the SQUIRE study, adding the anti-epidermal growth factor receptor (EGFR) IgG1 antibody necitumumab to first-line gemcitabine and cisplatin (GC + N) in advanced squamous non-small-cell lung cancer (sqNSCLC) significantly improved overall survival (OS); the safety profile was acceptable. We explored data for the German subpopulation (N = 96) of SQUIRE patients with EGFR-expressing tumors. |