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    Adjuvant weekly girentuximab following nephrectomy for high-risk renal cell carcinoma: the ARISER randomized clinical trial.

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    Authors
    Chamie, K
    Donin, N
    Klöpfer, P
    Bevan, P
    Fall, B
    Wilhelm, O
    Störkel, S
    Said, J
    Gambla, M
    Hawkins, Robert E
    Jankilevich, G
    Kapoor, A
    Kopyltsov, E
    Staehler, M
    Taari, K
    Wainstein, A
    Pantuck, A
    Belldegrun, A
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    Issue Date
    2016-10-27
    
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    Abstract
    Girentuximab is a chimeric monoclonal antibody that binds carbonic anhydrase IX, a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). Its safety and activity in phase 2 studies prompted investigation into its use as adjuvant monotherapy in participants with high-risk ccRCC.
    Citation
    Adjuvant weekly girentuximab following nephrectomy for high-risk renal cell carcinoma: the ARISER randomized clinical trial. 2016 JAMA Oncol
    Journal
    JAMA Oncology
    URI
    http://hdl.handle.net/10541/620021
    DOI
    10.1001/jamaoncol.2016.4419
    PubMed ID
    27787547
    Type
    Article
    Language
    en
    ISSN
    2374-2445
    ae974a485f413a2113503eed53cd6c53
    10.1001/jamaoncol.2016.4419
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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