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    Morphological features of fascia lata in relation to fascia diseases.

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    Authors
    Szotek, S
    Dawidowicz, J
    Eyden, Brian P
    Matysiak, N
    Czogalla, A
    Dudzik, G
    Leśniewicz, A
    Maksymowicz, K
    Affiliation
    Department of Biomedical Engineering, Mechatronics and Theory of Mechanisms, Faculty of Mechanical Engineering , Wroclaw University of Science and Technology , Wroclaw , Poland
    Issue Date
    2016-10-20
    
    Metadata
    Show full item record
    Abstract
    Fascia lata is an important element of the fascial system, which forms the continuum of connective tissue throughout the body. This deep fascia envelops the entire thigh and hip area and its main function is to transmit mechanical forces generated by the musculoskeletal system of the lower extremities. Fascia lata is also known as a useful and easily harvested graft material. Despite its crucial role in lower extremity biomechanics and wide-ranging applications in plastic and reconstructive surgery, both the structure of fascia lata and particularly the cells populating this tissue are relatively unexplored and therefore poorly understood. The aim of this study was to characterize the main cell populations encountered within human fascia lata and to try to understand their role in health and diseases. Pathologically unchanged human fascia lata was obtained post mortem from adult males. The specimens were analyzed under light, electron, and confocal microscopy. On the basis of different visualization techniques, we were able to characterize in detail the cells populating human fascia lata. The main cells found were fibroblasts, fibrocytes, mast cells, cells showing myoid differentiation, nerve cells, and most interestingly, telocytes. Our results supplement the formerly inadequate information in the literature regarding the cellular components of deep fascial structure, may contribute to a better understanding of the pathogenesis of fascial disorders and improve fascia lata application as a graft material.
    Citation
    Morphological features of fascia lata in relation to fascia diseases. 2016:1-14 Ultrastruct Pathol
    Journal
    Ultrastructural Pathology
    URI
    http://hdl.handle.net/10541/620013
    DOI
    10.1080/01913123.2016.1239665
    PubMed ID
    27762645
    Type
    Article
    Language
    en
    ISSN
    1521-0758
    ae974a485f413a2113503eed53cd6c53
    10.1080/01913123.2016.1239665
    Scopus Count
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