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    Circulating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC.

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    Authors
    Crosbie, P
    Shah, R
    Krysiak, P
    Zhou, Cong
    Morris, Karen
    Tugwood, Jonathan D
    Booton, R
    Blackhall, Fiona H
    Dive, Caroline
    Affiliation
    Manchester Thoracic Oncology Centre, North West Lung Centre, University Hospital of South Manchester, Manchester
    Issue Date
    2016-07-25
    
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    Abstract
    Tumor recurrence after surgical resection of NSCLC obstructs long-term disease-free survival in approximately 50% of cases. Our data suggest that combining circulating tumor cell enumeration (as single cells or clusters) in tumor-draining pulmonary vein and peripheral blood (assessed by CellSearch) at the time of NSCLC surgery better identifies those patients at higher risk for lung cancer recurrence than does peripheral circulating tumor cell number alone.
    Citation
    Circulating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC. 2016: J Thorac Oncol
    Journal
    Journal of Thoracic Oncology
    URI
    http://hdl.handle.net/10541/619853
    DOI
    10.1016/j.jtho.2016.06.017
    PubMed ID
    27468936
    Type
    Article
    Language
    en
    ISSN
    1556-1380
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jtho.2016.06.017
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