Circulating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC.
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Authors
Crosbie, PShah, R
Krysiak, P
Zhou, Cong
Morris, Karen
Tugwood, Jonathan D
Booton, R
Blackhall, Fiona H
Dive, Caroline
Affiliation
Manchester Thoracic Oncology Centre, North West Lung Centre, University Hospital of South Manchester, ManchesterIssue Date
2016-07-25
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Tumor recurrence after surgical resection of NSCLC obstructs long-term disease-free survival in approximately 50% of cases. Our data suggest that combining circulating tumor cell enumeration (as single cells or clusters) in tumor-draining pulmonary vein and peripheral blood (assessed by CellSearch) at the time of NSCLC surgery better identifies those patients at higher risk for lung cancer recurrence than does peripheral circulating tumor cell number alone.Citation
Circulating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC. 2016: J Thorac OncolJournal
Journal of Thoracic OncologyDOI
10.1016/j.jtho.2016.06.017PubMed ID
27468936Type
ArticleLanguage
enISSN
1556-1380ae974a485f413a2113503eed53cd6c53
10.1016/j.jtho.2016.06.017
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