Circulating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC.
Tugwood, Jonathan D
Blackhall, Fiona H
AffiliationManchester Thoracic Oncology Centre, North West Lung Centre, University Hospital of South Manchester, Manchester
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AbstractTumor recurrence after surgical resection of NSCLC obstructs long-term disease-free survival in approximately 50% of cases. Our data suggest that combining circulating tumor cell enumeration (as single cells or clusters) in tumor-draining pulmonary vein and peripheral blood (assessed by CellSearch) at the time of NSCLC surgery better identifies those patients at higher risk for lung cancer recurrence than does peripheral circulating tumor cell number alone.
CitationCirculating tumor cells detected in the tumor-draining pulmonary vein are associated with disease recurrence after surgical resection of NSCLC. 2016: J Thorac Oncol
JournalJournal of Thoracic Oncology