Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
Elliott, Rebecca M
West, Catharine M L
AffiliationThe Institute of Cancer Research, Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UK
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AbstractNumerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk have increased toxicity following radiotherapy.
CitationCommon genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity. 2016, 114 (10):1165-74 Br J Cancer
JournalBritish Journal of Cancer