Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
Authors
Ahmed, MDorling, L
Kerns, S
Fachal, L
Elliott, Rebecca M
Parliament, M
Rosenstein, B
Vega, A
Gómez-Caamaño, A
Barnett, G
Dearnaley, D
Hall, E
Sydes, M
Burnet, N
Pharoah, P
Eeles, R
West, Catharine M L
Affiliation
The Institute of Cancer Research, Royal Marsden NHS Foundation Trust, 123 Old Brompton Road, London SW7 3RP, UKIssue Date
2016-05-10
Metadata
Show full item recordAbstract
Numerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk have increased toxicity following radiotherapy.Citation
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity. 2016, 114 (10):1165-74 Br J CancerJournal
British Journal of CancerDOI
10.1038/bjc.2016.94PubMed ID
27070714Type
ArticleLanguage
enISSN
1532-1827ae974a485f413a2113503eed53cd6c53
10.1038/bjc.2016.94