• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsProfilesView

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Immunotherapy with checkpoint inhibitors for lung cancer: novel agents, biomarkers and paradigms.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Monteiro, I
    Califano, Raffaele
    Mountzios, G
    de Mello, R
    Affiliation
    Department of Medicine, Faculty of Medicine, University of Porto, Porto, Portugal
    Issue Date
    2016-02
    
    Metadata
    Show full item record
    Abstract
    Despite recent advances, prognosis of patients with advanced lung cancer remains dismal. Owing to a better understanding of the interactions between immune system and tumor cells, immunotherapy has emerged as a promising therapeutic strategy. After the recent approval of nivolumab and the promising results with other immune checkpoint inhibitors, combination strategies are now subject of intensive research. Notwithstanding these successes, immunotherapy still holds significant drawbacks. As the target shifts from tumor cells to the tumor microenvironment, treatment paradigms are changing and several improvements are needed for optimal use in clinical practice. Robust biomarkers for patient selection and a reliable way of evaluating treatment response are high priorities. Herein we review current data on immune checkpoint inhibitors for lung cancer treatment.
    Citation
    Immunotherapy with checkpoint inhibitors for lung cancer: novel agents, biomarkers and paradigms. 2016, 12 (4):551-64 Future Oncol
    Journal
    Future Oncology
    URI
    http://hdl.handle.net/10541/600546
    DOI
    10.2217/fon.15.309
    PubMed ID
    26776915
    Type
    Article
    Language
    en
    ISSN
    1744-8301
    ae974a485f413a2113503eed53cd6c53
    10.2217/fon.15.309
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • Immune Checkpoint Therapy in Non-Small Cell Lung Cancer.
    • Authors: Marrone KA, Brahmer JR
    • Issue date: 2016 Mar-Apr
    • Checkpoint inhibitors in breast cancer: hype or promise?
    • Authors: McArthur HL
    • Issue date: 2016 Jun
    • Immune checkpoint inhibitors in lung cancer: past, present and future.
    • Authors: Seetharamu N, Budman DR, Sullivan KM
    • Issue date: 2016 May
    • [Non-Small Cell Lung Cancer - from Immunobiology to Immunotherapy].
    • Authors: Bílek O, Bohovicová L, Demlová R, Poprach A, Lakomý R, Zdražilová-Dubská L
    • Issue date: 2016 Fall
    • Endocrinopathies induced by immune-checkpoint inhibitors in advanced non-small cell lung cancer.
    • Authors: Rossi E, Sgambato A, De Chiara G, Casaluce F, Losanno T, Sacco PC, Santabarbara G, Gridelli C
    • Issue date: 2016
    DSpace software (copyright © 2002 - 2025)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.