Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis.
Authors
Renehan, Andrew GMalcomson, L
Emsley, R
Gollins, S
Maw, A
Myint, A
Rooney, P
Susnerwala, S
Blower, Anthony
Saunders, Mark P
Wilson, Malcolm S
Scott, N
O'Dwyer, Sarah T
Affiliation
Institute of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UKIssue Date
2015-12-16
Metadata
Show full item recordAbstract
Induction of a clinical complete response with chemoradiotherapy, followed by observation via a watch-and-wait approach, has emerged as a management option for patients with rectal cancer. We aimed to address the shortage of evidence regarding the safety of the watch-and-wait approach by comparing oncological outcomes between patients managed by watch and wait who achieved a clinical complete response and those who had surgical resection (standard care).Citation
Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis. 2015: Lancet OncolJournal
The Lancet OncologyDOI
10.1016/S1470-2045(15)00467-2PubMed ID
26705854Type
ArticleLanguage
enISSN
1474-5488ae974a485f413a2113503eed53cd6c53
10.1016/S1470-2045(15)00467-2
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