Metastasis and oxidative stress: are antioxidants a metabolic driver of progression?
dc.contributor.author | Peiris-Pagès, Maria | |
dc.contributor.author | Martinez-Outschoorn, U | |
dc.contributor.author | Sotgia, Federica | |
dc.contributor.author | Lisanti, Michael P | |
dc.date.accessioned | 2016-01-12T09:48:03Z | en |
dc.date.available | 2016-01-12T09:48:03Z | en |
dc.date.issued | 2015-12-01 | en |
dc.identifier.citation | Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression? 2015, 22 (6):956-8 Cell Metab | en |
dc.identifier.issn | 1932-7420 | en |
dc.identifier.pmid | 26636492 | en |
dc.identifier.doi | 10.1016/j.cmet.2015.11.008 | en |
dc.identifier.uri | http://hdl.handle.net/10541/593303 | en |
dc.description.abstract | The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succeed in their purpose to metastasize. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to Cell metabolism | en |
dc.title | Metastasis and oxidative stress: are antioxidants a metabolic driver of progression? | en |
dc.type | Article | en |
dc.contributor.department | The Breast Cancer Now Research Unit, Institute of Cancer Sciences, CRUK Manchester Institute, Paterson Building, University of Manchester, Manchester M20 | en |
dc.identifier.journal | Cell Metabolism | en |
html.description.abstract | The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succeed in their purpose to metastasize. |