Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial.
Authors
Wang-Gillam, ALi, C
Bodoky, G
Dean, A
Shan, Y
Jameson, G
Macarulla, T
Lee, K
Cunningham, D
Blanc, J
Hubner, Richard A
Chiu, C
Schwartsmann, G
Siveke, J
Braiteh, F
Moyo, V
Belanger, B
Dhindsa, N
Bayever, E
Von Hoff, D
Chen, L
Affiliation
Washington University School of Medicine, St Louis, MO, USAIssue Date
2015-11-29
Metadata
Show full item recordAbstract
Nanoliposomal irinotecan showed activity in a phase 2 study in patients with metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based therapies. We assessed the effect of nanoliposomal irinotecan alone or combined with fluorouracil and folinic acid in a phase 3 trial in this population.Citation
Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial. 2015: LancetJournal
LancetDOI
10.1016/S0140-6736(15)00986-1PubMed ID
26615328Type
ArticleLanguage
enISSN
1474-547Xae974a485f413a2113503eed53cd6c53
10.1016/S0140-6736(15)00986-1
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