Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours.
Authors
Monaghan, Phillip JLamarca, Angela
Valle, Juan W
Hubner, Richard A
Mansoor, Was
Trainer, Peter J
Darby, D
Affiliation
The Christie Pathology Partnership, The Christie NHS Foundation Trust, ManchesterIssue Date
2015-11-26
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Show full item recordAbstract
Chromogranin-A (CgA) and -B (CgB) are markers for monitoring disease status in patients with gastroenteropancreatic neuroendocrine tumours (NETs). These are specialised diagnostic tests often necessitating referral of specimens to a supra-regional assay service (SAS) laboratory for analysis. The aim of this audit was to assess if measurement of either plasma CgA or CgB alone provides sufficient clinical information in comparison to the current practice of measuring both markers together.Citation
Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours. 2015: Clin.EndocrinolJournal
Clinical EndocrinologyDOI
10.1111/cen.12985PubMed ID
26608723Type
ArticleLanguage
enISSN
1365-2265ae974a485f413a2113503eed53cd6c53
10.1111/cen.12985
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