Show simple item record

dc.contributor.authorBarraclough, Lisa H
dc.contributor.authorField, Catherine
dc.contributor.authorWieringa, Gilbert E
dc.contributor.authorSwindell, Ric
dc.contributor.authorLivsey, Jacqueline E
dc.contributor.authorDavidson, Susan E
dc.date.accessioned2009-04-01T23:19:23Z
dc.date.available2009-04-01T23:19:23Z
dc.date.issued2008-12
dc.identifier.citationEstimation of renal function -- what is appropriate in cancer patients? 2008, 20 (10):721-6 Clin Oncol (R Coll Radiol)en
dc.identifier.issn0936-6555
dc.identifier.pmid18995170
dc.identifier.doi10.1016/j.clon.2008.09.004
dc.identifier.urihttp://hdl.handle.net/10541/58715
dc.description.abstractAIMS: To compare the accuracy of renal assessment in patients with cancer using radioisotope glomerular filtration rate (GFR), urine collection for creatinine clearance, Cockroft-Gault, Modification of Diet in Renal Disease (MDRD) and Wright formulae. MATERIALS AND METHODS: Measurements of isotope GFR from 367 patients were compared with estimates from the described methods (Cockroft-Gault, MDRD, Wright). An analysis including a further 252 patients with an isotope GFR < or = 50 ml/min was also carried out. RESULTS: The Wright formula was the most accurate form of estimating renal function for the first study group. The formulae were similar in accuracy in the second study group. CONCLUSIONS: The Wright formula is the most accurate form of estimation of renal function in comparison with the isotope GFR for cancer patients. When there is a large proportion of patients with a low isotope GFR (< or = 50 ml/min), the formulae have similar accuracy.
dc.language.isoenen
dc.subjectGFRen
dc.subjectRenal Canceren
dc.subjectRenal Function Assessmenten
dc.subjectCanceren
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAlgorithms
dc.subject.meshChlorides
dc.subject.meshChromium Compounds
dc.subject.meshChromium Radioisotopes
dc.subject.meshCreatinine
dc.subject.meshDiet
dc.subject.meshFemale
dc.subject.meshGlomerular Filtration Rate
dc.subject.meshHumans
dc.subject.meshKidney
dc.subject.meshKidney Diseases
dc.subject.meshKidney Function Tests
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasms
dc.subject.meshROC Curve
dc.subject.meshRegression Analysis
dc.subject.meshYoung Adult
dc.titleEstimation of renal function -- what is appropriate in cancer patients?en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Oncology, Christie Hospital, Manchester, UK. lisahelenbone@hotmail.comen
dc.identifier.journalClinical Oncologyen
html.description.abstractAIMS: To compare the accuracy of renal assessment in patients with cancer using radioisotope glomerular filtration rate (GFR), urine collection for creatinine clearance, Cockroft-Gault, Modification of Diet in Renal Disease (MDRD) and Wright formulae. MATERIALS AND METHODS: Measurements of isotope GFR from 367 patients were compared with estimates from the described methods (Cockroft-Gault, MDRD, Wright). An analysis including a further 252 patients with an isotope GFR < or = 50 ml/min was also carried out. RESULTS: The Wright formula was the most accurate form of estimating renal function for the first study group. The formulae were similar in accuracy in the second study group. CONCLUSIONS: The Wright formula is the most accurate form of estimation of renal function in comparison with the isotope GFR for cancer patients. When there is a large proportion of patients with a low isotope GFR (< or = 50 ml/min), the formulae have similar accuracy.


Files in this item

This item appears in the following Collection(s)

Show simple item record