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    Impact of skeletal complications on patients' quality of life, mobility, and functional independence.

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    Authors
    Costa, Luis
    Badia, Xavier
    Chow, Edward
    Lipton, Allan
    Wardley, Andrew M
    Affiliation
    Instituto de Medicina Molecular-Lisboa, Servico de Oncologia, Hospital de Santa Maria, Av Professor Egaz Moniz, Lisbon, 1649-039, Portugal. luiscosta.p@netcabo.pt
    Issue Date
    2008-08
    
    Metadata
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    Abstract
    INTRODUCTION: Skeletal-related events (SREs) from malignant bone disease cause considerable morbidity and can dramatically reduce patients' quality of life. DISCUSSION: Pathologic fractures often require surgical intervention and palliative radiotherapy. Thus, patients suffer impaired mobility, loss of functional independence, and diminished health-related quality of life (HRQOL). Bisphosphonates can delay the onset and reduce the incidence of SREs and have become the standard of care for the treatment of malignant bone disease; however, minimal information on the effects of bisphosphonate treatment on HRQOL is available. Targeted HRQOL assessments for patients with malignant bone disease are currently under development and are discussed herein.
    Citation
    Impact of skeletal complications on patients' quality of life, mobility, and functional independence. 2008, 16 (8):879-89 Support Care Cancer
    Journal
    Supportive Care in Cancer
    URI
    http://hdl.handle.net/10541/58692
    DOI
    10.1007/s00520-008-0418-0
    PubMed ID
    18392862
    Type
    Article
    Language
    en
    ISSN
    0941-4355
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00520-008-0418-0
    Scopus Count
    Collections
    All Christie Publications
    Medical Oncology

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