Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma.
Affiliation
Plastic Surgery Unit, Canniesburn Hospital, Glasgow Royal Infirmary, Glasgow, United Kingdom.Issue Date
2008-07
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Show full item recordAbstract
BACKGROUND: The aim of this study was to ascertain which factors determine success of sentinel node biopsy (SNB). METHODS: We conducted a retrospective review of 121 patients with head and neck squamous cell carcinoma undergoing SNB to stage the neck. All patients underwent the triple-diagnostic procedure of preoperative lymphoscintigraphy, intraoperative blue dye, and a gamma probe. Factors contributing to failure of SNB were identified. RESULTS: SNB was unsuccessful in 12 of 121 patients (10%). Seven of the 12 patients had cT1/cT2 tumors, and 6 of these were located in the floor of mouth. SN identification was more likely to be successful in patients with cN0 necks, but this did not reach statistical significance (92% vs 84%, p = .268). Factors associated with failure included T classification (p = .01), tumor site (p = .05), and negative preoperative lymphoscintigraphy (p = .0174). CONCLUSION: Successful sentinel lymph node harvest is related to primary tumor site, T classification, and the presence of nodes on preoperative lymphoscintigraphy.Citation
Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma. 2008, 30 (7):858-62 Head NeckJournal
Head & NeckDOI
10.1002/hed.20787PubMed ID
18302276Type
ArticleLanguage
enISSN
1097-0347ae974a485f413a2113503eed53cd6c53
10.1002/hed.20787