Intranasal human growth hormone (hGH) induces IGF-I levels comparable to subcutaneous injection with lower systemic exposure to hGH in healthy volunteers.
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Critical Pharmaceuticals Limited, BioCity Nottingham, Pennyfoot St, NottinghamIssue Date
2015-10-01
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The development of an improved, efficacious hGH product administered by a non-injectable route of delivery such as the nasal route is highly desirable. We have developed a novel nasal hGH product (CP024) that showed excellent nasal absorption in animal models, however translation of these results into the clinical setting is essential, as past attempts to develop such formulations by other groups have been unable to induce IGF-1 in man.Citation
Intranasal human growth hormone (hGH) induces IGF-I levels comparable to subcutaneous injection with lower systemic exposure to hGH in healthy volunteers. 2015:jc20144146 J Clin Endocrinol MetabJournal
Journal of Clinical Endocrinology and MetabolismDOI
10.1210/jc.2014-4146PubMed ID
26425883Type
ArticleLanguage
enISSN
1945-7197ae974a485f413a2113503eed53cd6c53
10.1210/jc.2014-4146
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