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    Antagonism of aminoacid transport in primary CD4 T cells by HIV-1 Vpu.

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    Authors
    Matheson, N
    Wals, K
    Weekes, M
    Rapiteanu, R
    Vigan, R
    Antrobus, R
    Smith, Duncan L
    Neil, S
    Lehner, P
    Affiliation
    Department of Medicine, University of Cambridge, Cambridge, UK.
    Issue Date
    2015-02-26
    
    Metadata
    Show full item record
    Abstract
    Less than 100 years since it was first transmitted to the human population HIV-1 infects more than 30 million people worldwide and causes almost 2 million AIDS-related deaths every year. Viruses manipulate cellular genes and pathways to benefit their survival, and the study of cell surface proteins downregulated by viruses has provided insights into both viral pathogenesis and crucial aspects of cell biology. We aimed to identify novel cell surface proteins targeted for downregulation by HIV-1.
    Citation
    Antagonism of aminoacid transport in primary CD4 T cells by HIV-1 Vpu. 2015, 385 Suppl 1:S66 Lancet
    Journal
    Lancet
    URI
    http://hdl.handle.net/10541/579033
    DOI
    10.1016/S0140-6736(15)60381-6
    PubMed ID
    26312888
    Type
    Article
    Language
    en
    ISSN
    1474-547X
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0140-6736(15)60381-6
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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