• Evaluation and prognostic significance of circulating tumor cells in patients with non-small-cell lung cancer.

      Krebs, Matthew G; Sloane, Robert; Priest, Lynsey; Lancashire, Lee J; Hou, Jian-Mei; Greystoke, Alastair; Ward, Timothy H; Ferraldeschi, Roberta; Hughes, Andrew; Clack, Glen; et al. (2011-04-20)
      Lung cancer is the leading cause of cancer-related death worldwide. Non-small-cell lung cancer (NSCLC) lacks validated biomarkers to predict treatment response. This study investigated whether circulating tumor cells (CTCs) are detectable in patients with NSCLC and what their ability might be to provide prognostic information and/or early indication of patient response to conventional therapy.