• Long-term safety of growth hormone replacement after CNS irradiation.

      Mackenzie, S; Craven, T; Gattamaneni, Rao; Swindell, Ric; Shalet, Stephen M; Brabant, Georg E; Department of Endocrinology, The Christie, Manchester Academic Health Science Centre, Wilmslow Road, Manchester M20 4BX, United Kingdom. (2011-09)
      Radiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.