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    Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial.

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    Authors
    Thatcher, Nick
    Hirsch, F
    Luft, A
    Szczesna, A
    Ciuleanu, T
    Dediu, M
    Ramlau, R
    Galiulin, R
    Bálint, B
    Losonczy, G
    Kazarnowicz, A
    Park, K
    Schumann, C
    Reck, M
    Depenbrock, H
    Nanda, S
    Kruljac-Letunic, A
    Kurek, R
    Paz-Ares, L
    Socinski, M
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    Affiliation
    The Christie Hospital, Manchester, UK.
    Issue Date
    2015-07
    
    Metadata
    Show full item record
    Abstract
    Necitumumab is a second-generation, recombinant, human immunoglobulin G1 EGFR antibody. In this study, we aimed to compare treatment with necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone in patients with previously untreated stage IV squamous non-small-cell lung cancer.
    Citation
    Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial. 2015, 16 (7):763-74 Lancet Oncol
    Journal
    The Lancet Oncology
    URI
    http://hdl.handle.net/10541/560896
    DOI
    10.1016/S1470-2045(15)00021-2
    PubMed ID
    26045340
    Type
    Article
    Language
    en
    ISSN
    1474-5488
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1470-2045(15)00021-2
    Scopus Count
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