Affiliation
Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.Issue Date
2008-09
Metadata
Show full item recordAbstract
Reporting in Molecular Cell, Sheridan et al. (2008) and Breckenridge et al. (2008) show that mitochondrial fragmentation is not required to induce cell death. Meanwhile, Yamaguchi et al. show that proapoptotic Bcl-2 family members promote cytochrome c mobilization through Opa1-mediated cristae remodeling. Therefore, the connection between mitochondrial structure and apoptosis is more complex than previously imagined.Citation
Mitochondrial dynamics and apoptosis: a painful separation. 2008, 15 (3):341-3 Dev. CellJournal
Developmental CellDOI
10.1016/j.devcel.2008.08.011PubMed ID
18804432Type
ArticleLanguage
enISSN
1534-5807ae974a485f413a2113503eed53cd6c53
10.1016/j.devcel.2008.08.011
Scopus Count
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