Decline in CA19-9 during chemotherapy predicts survival in four independent cohorts of patients with inoperable bile duct cancer.
Authors
Grunnet, MChristensen, I
Lassen, U
Jensen, L
Lydolph, M
Knox, J
McNamara, Mairéad G
Jitlal, M
Wasan, H
Bridgewater, J
Valle, Juan W
Mau-Sorensen, M
Affiliation
Dept. of Oncology, Rigshospitalet, Blegdamsvej 9, DK2100 Copenhagen O, DenmarkIssue Date
2015-07
Metadata
Show full item recordAbstract
Carbohydrate associated antigen (CA19-9) has been approved by the FDA as a biomarker for monitoring treatment effect in pancreatic cancer. However, the value of serum CA19-9 as a biomarker of response to chemotherapy in bile duct cancer is unclear. The aim of this study was to determine if a decline in CA19-9 (CA19-9 response) during chemotherapy is predictive of survival in patients with inoperable bile duct cancer.Citation
Decline in CA19-9 during chemotherapy predicts survival in four independent cohorts of patients with inoperable bile duct cancer. 2015, 51 (11):1381-8 Eur J CancerJournal
European Journal of CancerDOI
10.1016/j.ejca.2015.04.011PubMed ID
25971532Type
ArticleLanguage
enISSN
1879-0852ae974a485f413a2113503eed53cd6c53
10.1016/j.ejca.2015.04.011
Scopus Count
Collections
Related articles
- The clinical value of serum CEA, CA19-9, and CA242 in the diagnosis and prognosis of pancreatic cancer.
- Authors: Ni XG, Bai XF, Mao YL, Shao YF, Wu JX, Shan Y, Wang CF, Wang J, Tian YT, Liu Q, Xu DK, Zhao P
- Issue date: 2005 Mar
- CA19-9 as a prognostic factor in inoperable pancreatic cancer: the implication for clinical trials.
- Authors: Maisey NR, Norman AR, Hill A, Massey A, Oates J, Cunningham D
- Issue date: 2005 Oct 3
- Prognostic Impact of the Initial Postoperative CA19-9 Level in Patients with Extrahepatic Bile Duct Cancer.
- Authors: Kato Y, Takahashi S, Gotohda N, Konishi M
- Issue date: 2016 Aug
- Elevated perioperative serum CA 19-9 levels are independent predictors of poor survival in patients with resectable cholangiocarcinoma.
- Authors: Kondo N, Murakami Y, Uemura K, Sudo T, Hashimoto Y, Sasaki H, Sueda T
- Issue date: 2014 Sep
- CA19-9 as the most significant prognostic indicator of metastatic colorectal cancer.
- Authors: Wang WS, Lin JK, Chiou TJ, Liu JH, Fan FS, Yen CC, Lin TC, Jiang JK, Yang SH, Wang HS, Chen PM
- Issue date: 2002 Jan-Feb