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    Shading correction algorithm for improvement of cone-beam CT images in radiotherapy.

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    Authors
    Marchant, Thomas E
    Moore, Christopher J
    Rowbottom, Carl G
    Mackay, Ranald I
    Williams, Peter C
    Affiliation
    North Western Medical Physics, Christie Hospital NHS Foundation Trust, Manchester, UK. tom.marchant@physics.cr.man.ac.uk
    Issue Date
    2008-10-21
    
    Metadata
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    Abstract
    Cone-beam CT (CBCT) images have recently become an established modality for treatment verification in radiotherapy. However, identification of soft-tissue structures and the calculation of dose distributions based on CBCT images is often obstructed by image artefacts and poor consistency of density calibration. A robust method for voxel-by-voxel enhancement of CBCT images using a priori knowledge from the planning CT scan has been developed and implemented. CBCT scans were enhanced using a low spatial frequency grey scale shading function generated with the aid of a planning CT scan from the same patient. This circumvents the need for exact correspondence between CBCT and CT and the process is robust to the appearance of unshared features such as gas pockets. Enhancement was validated using patient CBCT images. CT numbers in regions of fat and muscle tissue in the processed CBCT were both within 1% of the values in the planning CT, as opposed to 10-20% different for the original CBCT. Visual assessment of processed CBCT images showed improvement in soft-tissue visibility, although some cases of artefact introduction were observed.
    Citation
    Shading correction algorithm for improvement of cone-beam CT images in radiotherapy. 2008, 53 (20):5719-33 Phys Med Biol
    Journal
    Physics in Medicine and Biology
    URI
    http://hdl.handle.net/10541/55802
    DOI
    10.1088/0031-9155/53/20/010
    PubMed ID
    18824785
    Type
    Article
    Language
    en
    ISSN
    0031-9155
    ae974a485f413a2113503eed53cd6c53
    10.1088/0031-9155/53/20/010
    Scopus Count
    Collections
    All Christie Publications
    Christie Medical Physics and Engineering Research

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