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    X:Map: annotation and visualization of genome structure for Affymetrix exon array analysis.

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    Authors
    Yates, Tim
    Okoniewski, Michal J
    Miller, Crispin J
    Affiliation
    Cancer Research UK, Bioinformatics Group, Paterson Institute for Cancer Research, The University of Manchester, Christie Hospital Site, Wilmslow Road, Withington, Manchester, M20 4BX, UK.
    Issue Date
    2008-01
    
    Metadata
    Show full item record
    Abstract
    Affymetrix exon arrays aim to target every known and predicted exon in the human, mouse or rat genomes, and have reporters that extend beyond protein coding regions to other areas of the transcribed genome. This combination of increased coverage and precision is important because a substantial proportion of protein coding genes are predicted to be alternatively spliced, and because many non-coding genes are known also to be of biological significance. In order to fully exploit these arrays, it is necessary to associate each reporter on the array with the features of the genome it is targeting, and to relate these to gene and genome structure. X:Map is a genome annotation database that provides this information. Data can be browsed using a novel Google-maps based interface, and analysed and further visualized through an associated BioConductor package. The database can be found at http://xmap.picr.man.ac.uk.
    Citation
    X:Map: annotation and visualization of genome structure for Affymetrix exon array analysis. 2008, 36 (Database issue):D780-6 Nucleic Acids Res.
    Journal
    Nucleic Acids Research
    URI
    http://hdl.handle.net/10541/55037
    DOI
    10.1093/nar/gkm779
    PubMed ID
    17932061
    Type
    Article
    Language
    en
    ISSN
    1362-4962
    ae974a485f413a2113503eed53cd6c53
    10.1093/nar/gkm779
    Scopus Count
    Collections
    Applied Computational Biology and Bioinformatics
    All Paterson Institute for Cancer Research

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