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    First-in-human pharmacokinetic and pharmacodynamic study of the dual m-TORC 1/2 inhibitor, AZD2014.

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    Authors
    Basu, B
    Dean, Emma J
    Puglisi, M
    Greystoke, Alastair
    Ong, M
    Burke, W
    Cavallin, M
    Bigley, G
    Womack, C
    Harrington, E
    Green, S
    Oelmann, E
    de Bono, J
    Ranson, Malcolm R
    Banerji, U
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    Affiliation
    Drug Development Unit, The Institute of Cancer Research & The Royal Marsden
    Issue Date
    2015-03-24
    
    Metadata
    Show full item record
    Abstract
    AZD2014 is a novel, oral, m-TORC 1/2 inhibitor which has shown in-vitro and in-vivo efficacy across a range of preclinical human cancer models.
    Citation
    First-in-human pharmacokinetic and pharmacodynamic study of the dual m-TORC 1/2 inhibitor, AZD2014. 2015: Clin Cancer Res
    Journal
    Clinical Cancer Research
    URI
    http://hdl.handle.net/10541/550235
    DOI
    10.1158/1078-0432.CCR-14-2422
    PubMed ID
    25805799
    Type
    Article
    Language
    en
    ISSN
    1078-0432
    ae974a485f413a2113503eed53cd6c53
    10.1158/1078-0432.CCR-14-2422
    Scopus Count
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