• Cancers in Australia in 2010 attributable to and prevented by the use of combined oral contraceptives.

      Jordan, S; Wilson, L; Nagle, C; Green, Adèle C; Olsen, C; Bain, C; Pandeya, N; Whiteman, D; Webb, P; QIMR Berghofer Medical Research Institute, Queensland (2015-10)
      To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to combined oral contraceptive pill (OCP) use.
    • Cancers in Australia in 2010 attributable to and prevented by the use of menopausal hormone therapy.

      Jordan, S; Wilson, L; Nagle, C; Green, Adèle C; Olsen, C; Bain, C; Pandeya, N; Whiteman, D; Webb, P; QIMR Berghofer Medical Research Institute, Queensland (2015-10)
      To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to menopausal hormone therapy (MHT) use.
    • Cancers in Australia in 2010 attributable to modifiable factors: introduction and overview.

      Whiteman, D; Webb, P; Green, Adèle C; Neale, R; Fritschi, L; Bain, C; Parkin, D; Wilson, L; Olsen, C; Nagle, C; et al. (2015-10)
      To describe the approach underpinning a national project to estimate the numbers and proportions of cancers occurring in Australia in 2010 that are attributable to modifiable causal factors.
    • Cancers in Australia in 2010 attributable to modifiable factors: summary and conclusions.

      Whiteman, D; Webb, P; Green, Adèle C; Neale, R; Fritschi, L; Bain, C; Parkin, D; Wilson, L; Olsen, C; Nagle, C; et al. (2015-10)
      To estimate the numbers and proportions of cancers occurring in Australia in 2010 attributable to modifiable causal factors.
    • Cancers in Australia in 2010 attributable to total breastfeeding durations of 12 months or less by parous women.

      Jordan, S; Wilson, L; Nagle, C; Green, Adèle C; Olsen, C; Bain, C; Pandeya, N; Whiteman, D; Webb, P; QIMR Berghofer Medical Research Institute, Queensland (2015-10)
      To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to parous women having breastfed for total durations of ≤12 months.
    • Cancers prevented in Australia in 2010 through the consumption of aspirin.

      Wilson, L; Green, Adèle C; Kendall, B; Jordan, S; Nagle, C; Bain, C; Neale, R; Whiteman, D; QIMR Berghofer Medical Research Institute, Queensland (2015-10)
      To estimate the proportion and number of cancers in Australia in 2010 that may have been prevented from occurring due to daily use of aspirin in the population.
    • Hormonal and reproductive factors and incidence of basal cell carcinoma and squamous cell carcinoma in a large, prospective cohort.

      Olsen, C; Pandeya, N; Thompson, B; Dusingize, J; Subramaniam, P; Nagle, C; Green, Adèle C; Neale, R; Webb, P; Whiteman, D; et al. (2017-09-22)
    • How many cancer cases and deaths are potentially preventable? Estimates for Australia in 2013.

      Wilson, L; Antonsson, A; Green, Adèle C; Jordan, S; Kendall, B; Nagle, C; Neale, R; Olsen, C; Webb, P; Whiteman, D; et al. (2017-10-06)
      Cancer is a leading cause of disease burden in Australia, particularly fatal burden, accounting for an estimated thirty percent of deaths. Many cancers develop because of exposure to lifestyle and environmental factors that are potentially modifiable. We aimed to quantify the proportions and numbers of cancer deaths and cases in Australia in 2013 attributable to 20 modifiable factors in eight broad groupings that are established causes of cancer, namely: tobacco smoke (smoking and second-hand), dietary factors (low intake of fruit, non-starchy vegetables and dietary fibre; and high intake of red and processed meat), overweight/obesity, alcohol, physical inactivity, solar ultraviolet radiation, infections (seven agents), and reproductive factors (lack of breastfeeding, menopausal hormone therapy use, combined oral contraceptive use). We estimated population attributable fractions (PAF) using standard formulae incorporating exposure prevalence and relative risk data. Of all cancer deaths in Australia in 2013, approximately 38% overall (males 41%, females 34%) could be attributed to the factors assessed; the corresponding PAF for cancer cases was 33% (males 34%, females 32%). Tobacco smoke was the leading cause of cancer deaths and cases, with PAFs of 23 and 13%, respectively, followed by dietary factors (5% deaths/5% cases), overweight/obesity (5%/4%) and infections (5%/3%). Cancer sites with the highest numbers of potentially preventable deaths/cases were lung (n = 6,776/9,272), colorectum (n = 1,974/7,380) and cutaneous melanoma (n = 1,390/7,918). We estimate that about 16,700 cancer deaths and 41,200 cancer cases could be prevented in Australia each year if people's exposures to 20 causal factors were aligned with levels recommended to minimise cancer risk.