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A comparison of bolus chasing and static digital subtraction arteriography in peripheral vascular disease.Ashleigh, R J; Hufton, Alan P; Razzaq, R; MacDiarmaid-Gordon, L; Department of Radiology, South Manchester University Hospitals NHS Trust, UK. (2000-08)The purpose of this study was to compare the techniques of bolus chasing angiography (BCA) and digital subtraction angiography (DSA). 75 patients with symptomatic atherosclerotic peripheral vascular disease were randomly assigned to have their lower limbs examined by BCA or DSA. Dose-area product (DAP), time of examination and dose of contrast medium were measured. Staff doses were measured with personal electronic dosemeters. Image quality was assessed from the laser printed images. DSA produced better images of vessels below the inguinal ligament, particularly the crural vessels (1/76 vs 17/74 non-diagnostic examinations, p < 0.00001) but at a higher DAP (median 53.8 Gy cm2 vs 18.9 Gy cm2, p < 0.01). Contrast medium dose was higher with BCA (29.8 gI2 vs 25.3 gI2, p < 0.01). Staff doses per unit patient dose were 2.3-3.3 times higher with BCA than DSA. Because of the poor long-term prognosis of patients with peripheral vascular disease, the improved image quality obtained by DSA justifies the increased radiation dose.