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    Can a brief psychological intervention prevent anxiety or depressive disorders in cancer patients? A randomised controlled trial.

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    Authors
    Pitceathly, Carolyn
    Maguire, Peter
    Fletcher, I
    Parle, Michael
    Tomenson, B
    Creed, Francis
    Affiliation
    CRUK Psychological Medicine Group, Stanley House, Christie Hospital, Manchester.
    Issue Date
    2009-01-06
    
    Metadata
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    Abstract
    BACKGROUND: We tested whether a brief psychological intervention could prevent anxiety or depressive disorders among newly diagnosed cancer patients. PATIENTS AND METHODS: Patients free of anxiety or depressive disorder were randomised to receive immediate intervention (start of cancer treatment), delayed intervention (8 weeks after starting treatment) or usual care. They were stratified according to risk of developing anxiety or depressive disorders. Primary outcome was measured using a standardised psychiatric interview to detect any anxiety or depressive disorder at 6 and 12 months following the cancer diagnosis. Analyses used conditional odds logistic regression models adjusting for age, gender, concerns and past history to compare outcome of all intervention patients with usual care. RESULTS: A total of 465 patients were recruited. In all, 313 (79%) of the 397 well enough to be interviewed completed the study. At 12 months, there was no difference between the groups receiving the intervention and usual care [odds ratio (OR) = 0.69, 95% confidence interval (CI) 0.41-1.17, P = 0.17]. In high-risk patients, those who received the intervention were less likely to develop an anxiety or depressive disorder compared with those who received usual care (OR = 0.54, 95% CI 0.29-1.00, P = 0.050). In low-risk patients, there was no difference (OR = 1.50, 95% CI 0.51-4.43, P = 0.47). CONCLUSION: A brief intervention, delivered by nonspecialists, promoted adjustment among newly diagnosed cancer patients at high risk of developing anxiety or depressive disorders.
    Citation
    Can a brief psychological intervention prevent anxiety or depressive disorders in cancer patients? A randomised controlled trial. 2009: Ann. Oncol.
    Journal
    Annals of Oncology : official journal of the European Society for Medical Oncology / ESMO
    URI
    http://hdl.handle.net/10541/52873
    DOI
    10.1093/annonc/mdn708
    PubMed ID
    19126633
    Type
    Article
    Language
    en
    ISSN
    1569-8041
    ae974a485f413a2113503eed53cd6c53
    10.1093/annonc/mdn708
    Scopus Count
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    All Christie Publications

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