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Non-melanoma skin cancer treated with high-dose-rate brachytherapy: a review of literature.Delishaj, D; Rembielak, Agata; Manfredi, B; Ursino, S; Pasqualetti, F; Laliscia, C; Orlandi, F; Morganti, R; Fabrini, Maria G; Paiar, F; et al. (2016-12)The incidence of non-melanoma skin cancer (NMSC) has been increasing over the past 30 years. There are different treatment options and surgical excision is the most frequent treatment due to its low rates of recurrence. Radiotherapy is an effective alternative of surgery, and brachytherapy (BT) might be a better therapeutic option due to high radiation dose concentration to the tumor with rapid dose fall-off resulting in normal tissues sparing. The aim of this review was to evaluate the local control, toxicity, and cosmetic outcomes in NMSC treated with high-dose-rate BT (HDR-BT).