Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, placebo-controlled phase 3 trial.
Authors
Petrylak, DVogelzang, N
Budnik, N
Wiechno, P
Sternberg, C
Doner, K
Bellmunt, J
Burke, J
de Olza, M
Choudhury, Ananya
Gschwend, J
Kopyltsov, E
Flechon, A
Van As, N
Houede, N
Barton, D
Fandi, A
Jungnelius, U
Li, S
de Wit, R
Fizazi, K
Affiliation
Yale Cancer Center, Department of Medicine Division of Oncology, New Haven, CT, USAIssue Date
2015-03-02
Metadata
Show full item recordAbstract
Patients with metastatic castration-resistant prostate cancer have few treatment options. We investigated the safety and efficacy of lenalidomide, an immunomodulatory agent with anti-angiogenic properties, in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic castration-resistant prostate cancer.Citation
Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, placebo-controlled phase 3 trial. 2015: Lancet OncolJournal
The Lancet OncologyDOI
10.1016/S1470-2045(15)70025-2PubMed ID
25743937Type
ArticleLanguage
enISSN
1474-5488ae974a485f413a2113503eed53cd6c53
10.1016/S1470-2045(15)70025-2
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