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dc.contributor.authorSchuessler, H
dc.contributor.authorDavies, J V
dc.date.accessioned2015-01-02T15:25:02Z
dc.date.available2015-01-02T15:25:02Z
dc.date.issued1983-03
dc.identifier.citationRadiation-induced reduction reactions with bovine serum albumin. 1983, 43 (3):291-301 Int J Radiat Biol Relat Stud Phys Chem Meden
dc.identifier.issn0020-7616
dc.identifier.pmid6601078
dc.identifier.urihttp://hdl.handle.net/10541/337769
dc.description.abstractThe reduction of bovine serum albumin (BSA) by hydrated electrons, formate and ethanol radicals leads to the formation of S-S-radicals. The reaction of the hydrated electrons becomes faster, if BSA was preirradiated in the presence of formate or ethanol, but the rate does not change if radiolysis is done in the presence of t-butanol or without scavenger. The reduction of BSA by formate radicals is 10 times slower but gives a higher yield of S-S-radicals than by hydrated electrons. The rate and yield of the reduction by the formate radicals are increased by preirradiation of BSA. The reduction by ethanol radicals is five times slower than by formate radicals and gives lower yields of S-S-radicals which are increased by preirradiation. All rates and yields of the reduction reactions are decreased by changing the pH from 6.3 to 7.3.
dc.language.isoenen
dc.rightsArchived with thanks to International journal of radiation biology and related studies in physics, chemistry, and medicineen
dc.subject.meshButanols
dc.subject.meshDose-Response Relationship, Radiation
dc.subject.meshEthanol
dc.subject.meshFormates
dc.subject.meshOxidation-Reduction
dc.subject.meshParticle Accelerators
dc.subject.meshPulse Radiolysis
dc.subject.meshSerum Albumin, Bovine
dc.titleRadiation-induced reduction reactions with bovine serum albumin.en
dc.typeArticleen
dc.contributor.departmentInstitut fur Radiologie der Universitat Erlangen-Nurnberg, D-8520 Erlangen, FR Germanyen
dc.identifier.journalInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicineen
html.description.abstractThe reduction of bovine serum albumin (BSA) by hydrated electrons, formate and ethanol radicals leads to the formation of S-S-radicals. The reaction of the hydrated electrons becomes faster, if BSA was preirradiated in the presence of formate or ethanol, but the rate does not change if radiolysis is done in the presence of t-butanol or without scavenger. The reduction of BSA by formate radicals is 10 times slower but gives a higher yield of S-S-radicals than by hydrated electrons. The rate and yield of the reduction by the formate radicals are increased by preirradiation of BSA. The reduction by ethanol radicals is five times slower than by formate radicals and gives lower yields of S-S-radicals which are increased by preirradiation. All rates and yields of the reduction reactions are decreased by changing the pH from 6.3 to 7.3.


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