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    Bowel disease after radiotherapy.

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    Authors
    Schofield, Philip F
    Holden, D
    Carr, N D
    Affiliation
    Christie Hospital and Holt Radium Institute, Manchester M20 9BX
    Issue Date
    1983-06
    
    Metadata
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    Abstract
    The clinical presentation, operative findings and outcome in 40 patients who required surgery for bowel disease after radiotherapy are presented. The type of presentation varied according to the time after radiotherapy. In the first month, many patients had a proctitis but none required surgery. Five patients were operated on within one month, 2 for radiation-induced acute ileitis and 3 for exacerbations of pre-existing disease (diverticular disease 2, ulcerative colitis 1). The commonest time of presentation was between 3 and 18 months after radiotherapy, when 20 patients needed surgery for bowel disease caused by radiation-induced local ischaemia. Twelve of these patients had chronic perforation, 6 had severe rectal bleeding and 2 had painful anorectal ulceration. Fifteen patients presented between 2 and 24 years after radiotherapy, usually with incomplete intestinal obstruction due to a fibrous stricture, but 2 patients had rectal carcinoma. Wide resection of the involved bowel was the principal method of treatment but any anastomosis was protected by a proximal defunctioning stoma. There was no operative mortality but 10 patients have died subsequently. The danger of dismissing these patients as having incurable malignancy is stressed because, although the condition is infrequent, it is usually amenable to adequate surgery.
    Citation
    Bowel disease after radiotherapy. 1983, 76 (6):463-6 J R Soc Med
    Journal
    Journal of the Royal Society of Medicine
    URI
    http://hdl.handle.net/10541/337548
    PubMed ID
    6864719
    Type
    Article
    Language
    en
    ISSN
    0141-0768
    Collections
    All Christie Publications

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