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dc.contributor.authorPointon, R C S
dc.contributor.authorAskill, C
dc.contributor.authorHunter, Robin D
dc.contributor.authorWilkinson, Peter M
dc.date.accessioned2014-12-22T15:14:27Z
dc.date.available2014-12-22T15:14:27Z
dc.date.issued1983-07
dc.identifier.citationTreatment of advanced head and neck cancer using synchronous therapy with methotrexate and irradiation. 1983, 34 (4):459-62 Clin Radiolen
dc.identifier.issn0009-9260
dc.identifier.pmid6409492
dc.identifier.doi10.1016/S0009-9260(83)80246-3
dc.identifier.urihttp://hdl.handle.net/10541/337538
dc.description.abstractA pilot study of synchronous methotrexate and radiation therapy was carried out in 50 patients with advanced carcinoma of the head and neck, of whom 48 were assessable for response. Complete resolution of disease, maintained for 2 years, was achieved in 21 patients (45%), and in 19 out of 36 patients (53%) with carcinoma of the oropharynx and hypopharynx. The treatment was well tolerated, with acceptable morbidity.
dc.language.isoenen
dc.rightsArchived with thanks to Clinical radiologyen
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshCarcinoma, Squamous Cell
dc.subject.meshFemale
dc.subject.meshHead and Neck Neoplasms
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMethotrexate
dc.subject.meshMiddle Aged
dc.subject.meshPilot Projects
dc.subject.meshRadiotherapy, High-Energy
dc.titleTreatment of advanced head and neck cancer using synchronous therapy with methotrexate and irradiation.en
dc.typeArticleen
dc.contributor.departmentDepartments of Radiotherapy and Clinical Pharmacology, Christie Hospital & Holt Radium Institute, Manchesteren
dc.identifier.journalClinical Radiologyen
html.description.abstractA pilot study of synchronous methotrexate and radiation therapy was carried out in 50 patients with advanced carcinoma of the head and neck, of whom 48 were assessable for response. Complete resolution of disease, maintained for 2 years, was achieved in 21 patients (45%), and in 19 out of 36 patients (53%) with carcinoma of the oropharynx and hypopharynx. The treatment was well tolerated, with acceptable morbidity.


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