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A study of glial fibrillary acidic protein (GFAP) in childhood brain tumours.

dc.contributor.authorMarsden, Henry B
dc.contributor.authorKumar, Shant
dc.contributor.authorKahn, J
dc.contributor.authorAnderton, B J
dc.date.accessioned2014-12-22T15:36:23Z
dc.date.available2014-12-22T15:36:23Z
dc.date.issued1983-04-15
dc.identifier.citationA study of glial fibrillary acidic protein (GFAP) in childhood brain tumours. 1983, 31 (4):439-45 Int. J. Canceren
dc.identifier.issn0020-7136
dc.identifier.pmid6339423
dc.identifier.urihttp://hdl.handle.net/10541/337518
dc.description.abstractA retrospective study of 366 primary brain tumours in childhood has been carried out, GFAP was detected in juvenile astrocytoma (76/121), adult astrocytoma (34/78), malignant glioma (0/8), other astrocytic tumours (2/4) and medulloblastoma (0/101). In eight medulloblastomas scanty positive cells were seen but were regarded as reactive rather than neoplastic. The presence of GFAP was only found to be of prognostic value in adult astrocytoma, where its occurrence was associated with a more favourable outcome.
dc.language.isoenen
dc.rightsArchived with thanks to International journal of cancer. Journal international du canceren
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAstrocytoma
dc.subject.meshBrain Neoplasms
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshEpendymoma
dc.subject.meshGlial Fibrillary Acidic Protein
dc.subject.meshGlioma
dc.subject.meshHumans
dc.subject.meshImmunoenzyme Techniques
dc.subject.meshInfant
dc.subject.meshIntermediate Filament Proteins
dc.subject.meshMedulloblastoma
dc.subject.meshPrognosis
dc.subject.meshRetrospective Studies
dc.titleA study of glial fibrillary acidic protein (GFAP) in childhood brain tumours.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital, Manchester, M20 9BXen
dc.identifier.journalInternational Journal of Canceren
html.description.abstractA retrospective study of 366 primary brain tumours in childhood has been carried out, GFAP was detected in juvenile astrocytoma (76/121), adult astrocytoma (34/78), malignant glioma (0/8), other astrocytic tumours (2/4) and medulloblastoma (0/101). In eight medulloblastomas scanty positive cells were seen but were regarded as reactive rather than neoplastic. The presence of GFAP was only found to be of prognostic value in adult astrocytoma, where its occurrence was associated with a more favourable outcome.


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