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    Gastrointestinal involvement with myeloma.

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    Authors
    Benson, W J
    Scarffe, J Howard
    Houwen, B
    Crowther, Derek
    Affiliation
    Cancer Research Campaign, Department of Medical Oncology, Christie Hospital and Holt Radium Institute, Manchester
    Issue Date
    1983
    
    Metadata
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    Abstract
    A patient with IgA-k multiple myeloma is presented. There was initially a good response to chemotherapy but the patient later developed small intestinal obstruction. This was due to multiple polypoid plasmacytomas. The mesenteric nodes were also involved, and were found on immunofluorescence microscopy and flow cytometry with double fluorescent labelling to be composed of two separate populations of cells (IgA-k and IgG-k), one population having a diploid content of DNA and the other tetraploid. These two distinct cell populations differed in both proliferative characteristics and size. The findings are discussed and the literature relating to gastrointestinal involvement in plasma cell dyscrasias reviewed.
    Citation
    Gastrointestinal involvement with myeloma. 1983, 11 (4):256-62 Med Pediatr Oncol
    Journal
    Medical and Pediatric Oncology
    URI
    http://hdl.handle.net/10541/337511
    PubMed ID
    6888326
    Type
    Article
    Language
    en
    ISSN
    0098-1532
    Collections
    All Christie Publications

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