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dc.contributor.authorJames, Roger D
dc.contributor.authorJohnson, Richard J
dc.contributor.authorEddleston, Brian
dc.contributor.authorZheng, Guoliang
dc.contributor.authorJones, J M
dc.date.accessioned2014-12-09T12:12:26Z
dc.date.available2014-12-09T12:12:26Z
dc.date.issued1983-08
dc.identifier.citationPrognostic factors in locally recurrent rectal carcinoma treated by radiotherapy. 1983, 70 (8):469-72 Br J Surgen
dc.identifier.issn0007-1323
dc.identifier.pmid6871637
dc.identifier.urihttp://hdl.handle.net/10541/336984
dc.description.abstractAn analysis has been made of the symptomatic response and survival of 143 patients following radiotherapy for locally recurrent rectal cancer. Computerized tomography (CAT) was performed on 45 patients. Of 119 evaluable patients, 54 had a good response to radiotherapy, 29 a moderate response and 36 no apparent response. Median response was 9 and 3 months respectively in the good and moderate groups. Median survival was 15, 9 and 5 months for the three groups. Latent interval between surgery and radiotherapy appeared to be of prognostic importance. When this exceeded 2 yr median survival was 12 months compared with 7 months for patients with a latent interval of less than 2 yr. Tumour volume measured by computed tomography may have prognostic importance. Radiotherapy should be considered for most patients with symptomatic recurrence. Surgery might be combined with radiotherapy for selected groups of patients with good prognosis.
dc.language.isoenen
dc.rightsArchived with thanks to The British journal of surgeryen
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Recurrence, Local
dc.subject.meshPrognosis
dc.subject.meshRadiotherapy Dosage
dc.subject.meshRectal Neoplasms
dc.subject.meshTime Factors
dc.titlePrognostic factors in locally recurrent rectal carcinoma treated by radiotherapy.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital and Holt Radium Institute, Manchester M20 9BXen
dc.identifier.journalBritish Journal of Surgeryen
html.description.abstractAn analysis has been made of the symptomatic response and survival of 143 patients following radiotherapy for locally recurrent rectal cancer. Computerized tomography (CAT) was performed on 45 patients. Of 119 evaluable patients, 54 had a good response to radiotherapy, 29 a moderate response and 36 no apparent response. Median response was 9 and 3 months respectively in the good and moderate groups. Median survival was 15, 9 and 5 months for the three groups. Latent interval between surgery and radiotherapy appeared to be of prognostic importance. When this exceeded 2 yr median survival was 12 months compared with 7 months for patients with a latent interval of less than 2 yr. Tumour volume measured by computed tomography may have prognostic importance. Radiotherapy should be considered for most patients with symptomatic recurrence. Surgery might be combined with radiotherapy for selected groups of patients with good prognosis.


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