Show simple item record

dc.contributor.authorBrown, R A
dc.contributor.authorTomlinson, I W
dc.contributor.authorHill, C R
dc.contributor.authorWeiss, J B
dc.contributor.authorPhillips, P
dc.contributor.authorKumar, Shant
dc.date.accessioned2014-12-09T12:09:30Z
dc.date.available2014-12-09T12:09:30Z
dc.date.issued1983-06
dc.identifier.citationRelationship of angiogenesis factor in synovial fluid to various joint diseases. 1983, 42 (3):301-7 Ann Rheum Disen
dc.identifier.issn0003-4967
dc.identifier.pmid6859962
dc.identifier.urihttp://hdl.handle.net/10541/336981
dc.description.abstractA low-molecular-weight freely dialysable angiogenesis factor has been isolated from 49 synovial fluids obtained from patients with various joint diseases. An analysis of disease type and incidence of freely dialysable angiogenesis activity showed that the osteoarthrotic group had a significantly higher incidence than all the other groups (p = 0.0332). Angiogenesis factor has also been detected in a bound form in the retentates of fluids which gave positive results for dialysable factor. The possibility that an imbalance between carrier-bound and free factor may have a causative role in disease is discussed.
dc.language.isoenen
dc.rightsArchived with thanks to Annals of the rheumatic diseasesen
dc.subject.meshAngiogenesis Inducing Agents
dc.subject.meshChromatography, DEAE-Cellulose
dc.subject.meshDialysis
dc.subject.meshGrowth Substances
dc.subject.meshHumans
dc.subject.meshJoint Diseases
dc.subject.meshMolecular Weight
dc.subject.meshOsteoarthritis
dc.subject.meshSynovial Fluid
dc.titleRelationship of angiogenesis factor in synovial fluid to various joint diseases.en
dc.typeArticleen
dc.contributor.departmentDepartment of Rheumatology, University of Manchester Medical Schoolen
dc.identifier.journalAnnals of the Rheumatic Diseasesen
html.description.abstractA low-molecular-weight freely dialysable angiogenesis factor has been isolated from 49 synovial fluids obtained from patients with various joint diseases. An analysis of disease type and incidence of freely dialysable angiogenesis activity showed that the osteoarthrotic group had a significantly higher incidence than all the other groups (p = 0.0332). Angiogenesis factor has also been detected in a bound form in the retentates of fluids which gave positive results for dialysable factor. The possibility that an imbalance between carrier-bound and free factor may have a causative role in disease is discussed.


This item appears in the following Collection(s)

Show simple item record