Relationship of angiogenesis factor in synovial fluid to various joint diseases.
AffiliationDepartment of Rheumatology, University of Manchester Medical School
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AbstractA low-molecular-weight freely dialysable angiogenesis factor has been isolated from 49 synovial fluids obtained from patients with various joint diseases. An analysis of disease type and incidence of freely dialysable angiogenesis activity showed that the osteoarthrotic group had a significantly higher incidence than all the other groups (p = 0.0332). Angiogenesis factor has also been detected in a bound form in the retentates of fluids which gave positive results for dialysable factor. The possibility that an imbalance between carrier-bound and free factor may have a causative role in disease is discussed.
CitationRelationship of angiogenesis factor in synovial fluid to various joint diseases. 1983, 42 (3):301-7 Ann Rheum Dis
JournalAnnals of the Rheumatic Diseases
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