Relationship of angiogenesis factor in synovial fluid to various joint diseases.
AffiliationDepartment of Rheumatology, University of Manchester Medical School
MetadataShow full item record
AbstractA low-molecular-weight freely dialysable angiogenesis factor has been isolated from 49 synovial fluids obtained from patients with various joint diseases. An analysis of disease type and incidence of freely dialysable angiogenesis activity showed that the osteoarthrotic group had a significantly higher incidence than all the other groups (p = 0.0332). Angiogenesis factor has also been detected in a bound form in the retentates of fluids which gave positive results for dialysable factor. The possibility that an imbalance between carrier-bound and free factor may have a causative role in disease is discussed.
CitationRelationship of angiogenesis factor in synovial fluid to various joint diseases. 1983, 42 (3):301-7 Ann Rheum Dis
JournalAnnals of the Rheumatic Diseases
- Angiogenic factor from synovial fluid resembling that from tumours.
- Authors: Brown RA, Weiss JB, Tomlinson IW, Phillips P, Kumar S
- Issue date: 1980 Mar 29
- A low-molecular-weight angiogenic factor in cat retina.
- Authors: Kissun RD, Hill CR, Garner A, Phillips P, Kumar S, Weiss JB
- Issue date: 1982 Mar
- A study of angiogenesis factors from five different sources using a radioimmunoassay.
- Authors: Shahabuddin S, Kumar S, West D, Arnold F
- Issue date: 1985 Jan 15
- Serum and synovial fluid hydroxyproline fractions in microcrystalline arthritis and osteoarthritis.
- Authors: Manicourt D, Rao VH, Orloff S
- Issue date: 1979
- Bovine retinal angiogenesis factor is a small molecule (molecular mass less than 600).
- Authors: Elstow SF, Schor AM, Weiss JB
- Issue date: 1985 Jan