Randomized Phase III Trial of Amrubicin Versus Topotecan As Second-Line Treatment for Patients With Small-Cell Lung Cancer.
Authors
Von Pawel, JJotte, R
Spigel, D
O'Brien, M
Socinski, M
Mezger, J
Steins, M
Bosquée, L
Bubis, J
Nackaerts, K
Trigo, J
Clingan, P
Schütte, W
Lorigan, Paul C
Reck, M
Domine, M
Shepherd, F
Li, S
Renschler, M
Affiliation
Asklepios Fachkliniken Munchen-Gauting, GautingIssue Date
2014-11-10
Metadata
Show full item recordAbstract
Amrubicin, a third-generation anthracycline and potent topoisomerase II inhibitor, showed promising activity in small-cell lung cancer (SCLC) in phase II trials. This phase III trial compared the safety and efficacy of amrubicin versus topotecan as second-line treatment for SCLC.Citation
Randomized Phase III Trial of Amrubicin Versus Topotecan As Second-Line Treatment for Patients With Small-Cell Lung Cancer. 2014: J Clin OncolJournal
Journal of Clinical OncologyDOI
10.1200/JCO.2013.54.5392PubMed ID
25385727Type
ArticleLanguage
enISSN
1527-7755ae974a485f413a2113503eed53cd6c53
10.1200/JCO.2013.54.5392
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