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    Diabetes and cancer: 5 years into the recent controversy.

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    Authors
    Badrick, E
    Renehan, Andrew G
    Affiliation
    Institute of Population Health, University of Manchester, Manchester, UK.
    Issue Date
    2014-08
    
    Metadata
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    Abstract
    Diabetes and cancer are common chronic disorders. The literature has long recognised that type 2 diabetes (T2D) is associated with an increased incident risk of several cancer types, independent of the mutual risk factor, obesity. However, in June 2009, four papers were published simultaneously in Diabetologia, the official journal of the European Association for the Study of Diabetes, raising questions of a link between diabetes therapies, notably the long-acting insulin analogue, glargine, and increased cancer risk. These papers awakened an unprecedented debate in the diabetes community, drawing in cancer experts and bringing together representatives from these two large, traditionally non-intersecting, biomedical communities. This Current Perspective summarises the events that followed the 'breaking news' from summer 2009: the pitfalls encountered; the increased mutual understanding between diabetes and cancer researchers; and the direction of current research. Much of the debate on the clinical impact of this controversy has been played out in the diabetes literature: here, we update the oncology readership.
    Citation
    Diabetes and cancer: 5 years into the recent controversy. 2014, 50 (12):2119-25 Eur J Cancer
    Journal
    European Journal of Cancer
    URI
    http://hdl.handle.net/10541/332310
    DOI
    10.1016/j.ejca.2014.04.032
    PubMed ID
    24930060
    Type
    Article
    Language
    en
    ISSN
    1879-0852
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.ejca.2014.04.032
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